{"product_id":"nsj-fy12246-100ul","title":"hCG beta Antibody \/ Human chorionic gonadotropin beta, 100 ul","description":"\u003cp\u003ehCG beta antibody detects the beta subunit of human chorionic gonadotropin (hCG), a glycoprotein hormone produced primarily by placental trophoblast cells during pregnancy. hCG consists of alpha and beta subunits, with the beta subunit providing biological specificity distinct from other glycoprotein hormones such as LH, FSH, and TSH. hCG binds to the LH\/CG receptor to promote corpus luteum maintenance and progesterone production, supporting early pregnancy and implantation.\u003cbr\u003e\u003cbr\u003eResearch using hCG beta antibody spans reproductive biology, oncology, and endocrinology. In pregnancy, hCG beta serves as a key biomarker for implantation success, gestational health, and detection of ectopic pregnancy. Clinical tests measuring hCG beta levels form the basis of most pregnancy assays. Aberrant expression of hCG beta subunit also occurs in trophoblastic disease and germ cell tumors, where elevated levels are diagnostic markers.\u003cbr\u003e\u003cbr\u003eIn oncology, hCG beta is expressed in a range of non-trophoblastic tumors including bladder, breast, lung, and gastrointestinal cancers. Its expression correlates with poor prognosis and aggressive tumor behavior. The beta subunit has been implicated in tumor progression, invasion, and immune modulation, making it both a biomarker and a potential therapeutic target.\u003cbr\u003e\u003cbr\u003ehCG beta also plays a role in immunology, where it can modulate maternal immune tolerance during pregnancy. By influencing T-cell function and cytokine production, hCG beta contributes to maintaining maternal-fetal tolerance and preventing rejection of the semi-allogeneic fetus.\u003cbr\u003e\u003cbr\u003eAntibodies against hCG beta are validated for ELISA, immunohistochemistry, immunofluorescence, and western blot. These reagents support research into reproductive health, cancer diagnostics, and endocrine regulation. Clone-based antibodies provide high specificity for the beta subunit, avoiding cross-reactivity with the common alpha subunit shared by other glycoprotein hormones.\u003cbr\u003e\u003cbr\u003eNSJ Bioreagents supplies this hCG beta antibody for applications in reproductive biology, oncology, and clinical research.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51552414466328,"sku":"FY12246","price":449.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/nsj-fy12246-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}