{"product_id":"nsj-fy12075-100ul","title":"HNRNPM Antibody \/ heterogeneous nuclear ribonucleoprotein M, 100 ul","description":"\u003cp\u003eHNRNPM antibody recognizes heterogeneous nuclear ribonucleoprotein M, an RNA-binding protein involved in pre-mRNA processing and splicing regulation. HNRNPM is part of the hnRNP family, which associates with nascent transcripts to influence alternative splicing, stability, transport, and translation. This protein is widely expressed and contributes to the regulation of diverse gene expression programs in normal development and stress adaptation.\u003cbr\u003e\u003cbr\u003eResearch using HNRNPM antibody has linked the protein to cancer progression and metastasis. By regulating alternative splicing of genes related to epithelial-to-mesenchymal transition (EMT), HNRNPM promotes tumor invasiveness and metastatic potential. Elevated expression of HNRNPM has been associated with poor prognosis in breast, colorectal, and liver cancers. Its role in RNA processing makes it a critical factor in understanding how splicing dysregulation contributes to oncogenesis.\u003cbr\u003e\u003cbr\u003eBeyond cancer, HNRNPM has been implicated in immune function and neurobiology. Studies suggest roles in regulating splicing of immune-related transcripts and neuronal genes, connecting HNRNPM to autoimmune conditions and neurological disorders. Its widespread impact on RNA metabolism positions HNRNPM as an important regulator of cellular identity and function.\u003cbr\u003e\u003cbr\u003eAntibodies against HNRNPM are validated for western blot, immunoprecipitation, immunohistochemistry, and immunofluorescence. Researchers use these reagents to analyze HNRNPM expression, splicing complex assembly, and transcript-specific binding. Clone-based antibodies offer the specificity needed to study this protein within large multi-protein RNA processing complexes.\u003cbr\u003e\u003cbr\u003eNSJ Bioreagents offers this HNRNPM antibody for investigations into RNA splicing, cancer biology, and immune regulation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51552425935128,"sku":"FY12075","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_e546cfaa-faaa-46e1-ba0c-f5d469e1d700.jpg?v=1768354682","url":"https:\/\/danabiosci.com\/products\/nsj-fy12075-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}