{"product_id":"nsj-fy12014-100ug","title":"PITPNM1 Antibody \/ Phosphatidylinositol transfer protein membrane associated 1, 100 ug","description":"\u003cp\u003ePITPNM1 antibody detects Phosphatidylinositol transfer protein membrane associated 1, encoded by the PITPNM1 gene. Phosphatidylinositol transfer protein membrane associated 1 is a large multi-domain protein localized to membranes and involved in phosphoinositide signaling and vesicular trafficking. PITPNM1 antibody provides researchers with a reagent to study lipid metabolism, intracellular signaling, and membrane dynamics.\u003cbr\u003e\u003cbr\u003ePhosphatidylinositol transfer protein membrane associated 1 is part of the retinal degeneration B protein family. Research using PITPNM1 antibody has shown that it binds and transfers phosphatidylinositol and phosphatidic acid between membranes. This transfer activity regulates phosphoinositide pools that are critical for vesicular transport, endocytosis, and exocytosis. By maintaining lipid composition, PITPNM1 ensures membrane identity and function.\u003cbr\u003e\u003cbr\u003eStudies with PITPNM1 antibody have revealed that the protein localizes to the Golgi apparatus, endoplasmic reticulum, and plasma membrane. This localization supports its function in coordinating vesicular trafficking between secretory and endocytic pathways. PITPNM1 interacts with Rab and Arf proteins, integrating lipid metabolism with trafficking machinery. These findings highlight its role in cellular logistics and signaling.\u003cbr\u003e\u003cbr\u003ePhosphatidylinositol transfer protein membrane associated 1 has been linked to neuronal biology and retinal function. Research using PITPNM1 antibody has suggested that it contributes to photoreceptor maintenance, and mutations in related family members are associated with retinal degeneration. Dysregulation of PITPNM1 expression has also been implicated in cancer, where altered lipid signaling supports proliferation and survival. This underscores the significance of PITPNM1 in both physiology and pathology.\u003cbr\u003e\u003cbr\u003ePITPNM1 antibody is widely applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects expression in diverse tissues, immunohistochemistry reveals subcellular distribution in the Golgi and ER, and immunofluorescence highlights its role in vesicular trafficking. These approaches make PITPNM1 antibody a valuable tool in lipid biology and membrane trafficking research.\u003cbr\u003e\u003cbr\u003eBy supplying validated PITPNM1 antibody reagents, NSJ Bioreagents supports studies into phosphoinositide signaling, membrane dynamics, and disease. Detection of Phosphatidylinositol transfer protein membrane associated 1 provides researchers with insights into how lipid transfer proteins coordinate cellular processes.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51552430686488,"sku":"FY12014","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_98433a35-0a15-4912-a18e-bde3e1650347.jpg?v=1768354776","url":"https:\/\/danabiosci.com\/products\/nsj-fy12014-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}