{"product_id":"nsj-fy12008-100ul","title":"EXOC2 Antibody \/ Exocyst complex component 2, 100 ul","description":"\u003cp\u003eEXOC2 antibody detects exocyst complex component 2, a critical member of the octameric exocyst complex that regulates tethering of secretory vesicles to the plasma membrane. This protein, also known as Sec5, functions in exocytosis and polarized trafficking, ensuring cargo delivery to specific membrane domains. By organizing vesicle docking, EXOC2 plays a fundamental role in processes such as cell migration, epithelial polarity, and neurite outgrowth. Its interactions with Ral GTPases highlight its role in small GTPase-mediated trafficking control.\u003cbr\u003e\u003cbr\u003eResearch using EXOC2 antibody has connected this protein to cancer and neurological disorders. Overexpression of EXOC2 has been reported in several tumor types, where it may promote invasive behavior by enhancing targeted membrane addition and secretion of proteases. In neurons, altered exocyst function has been linked to impaired synaptic vesicle recycling and neurodevelopmental defects. Investigating EXOC2 therefore provides insight into both normal cellular organization and disease pathology.\u003cbr\u003e\u003cbr\u003eAntibodies against EXOC2 have been validated in western blot, immunohistochemistry, and immunoprecipitation. These tools help characterize exocyst assembly, subcellular localization, and interactions with signaling proteins. High-specificity clones are particularly valuable for distinguishing EXOC2 from related exocyst components within large multiprotein complexes.\u003cbr\u003e\u003cbr\u003eNSJ Bioreagents supplies this EXOC2 antibody for research applications in membrane trafficking, cancer biology, and neurobiology. Alternate names include exocyst complex component 2 antibody, Sec5 antibody, SEC5L1 antibody, and Sec5p antibody.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51552431112472,"sku":"FY12008","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_d843ee6b-c0d6-4fc2-a9b7-78e47b397d48.jpg?v=1768354785","url":"https:\/\/danabiosci.com\/products\/nsj-fy12008-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}