{"product_id":"nsj-f54440-0-08ml","title":"LYK5 Antibody \/ STRADA, 0.08 ml","description":"\u003cp\u003eLYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml","offer_id":51552520438040,"sku":"F54440-0.08ML","price":205.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1abed6f6-92f2-4605-99be-f8337c67b5db.jpg?v=1768356903","url":"https:\/\/danabiosci.com\/products\/nsj-f54440-0-08ml","provider":"Dana Bioscience","version":"1.0","type":"link"}