{"product_id":"nsj-f54217-0-05ml","title":"METTL14 Antibody \/ N-Terminal Region, 0.05 ml","description":"\u003cp\u003eN6-adenosine-methyltransferase subunit METTL14 is an N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.05 ml","offer_id":51552550551832,"sku":"F54217-0.05ML","price":205.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_03bc00dd-3ae9-4609-87a3-1d275855548f.jpg?v=1768357575","url":"https:\/\/danabiosci.com\/products\/nsj-f54217-0-05ml","provider":"Dana Bioscience","version":"1.0","type":"link"}