{"product_id":"nsj-f53772-0-4ml","title":"SHP2 Antibody \/ PTPN11, 0.4 ml","description":"\u003cp\u003eSHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552609763608,"sku":"F53772-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_f2992555-4093-4841-a1dd-dbd1b0b81bbf.jpg?v=1768358664","url":"https:\/\/danabiosci.com\/products\/nsj-f53772-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}