{"product_id":"nsj-f53608-0-1ml","title":"Cortactin Antibody, 0.1 ml","description":"\u003cp\u003eThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.1 ml","offer_id":51552613040408,"sku":"F53608-0.1ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_ceedeea9-10fb-4857-9b6a-ca49283acc1a.jpg?v=1768358736","url":"https:\/\/danabiosci.com\/products\/nsj-f53608-0-1ml","provider":"Dana Bioscience","version":"1.0","type":"link"}