{"product_id":"nsj-f53185-0-08ml","title":"LRRK2 Antibody, 0.08 ml","description":"\u003cp\u003ePositively regulates autophagy through a calcium- dependent activation of the CaMKK\/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Phosphorylates PRDX3. May also have GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml","offer_id":51552622641432,"sku":"F53185-0.08ML","price":205.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_744a70f5-d271-4c7e-b268-2bbe94118812.jpg?v=1768358981","url":"https:\/\/danabiosci.com\/products\/nsj-f53185-0-08ml","provider":"Dana Bioscience","version":"1.0","type":"link"}