{"product_id":"nsj-f50223-0-4ml","title":"LKB1 Antibody, 0.4 ml","description":"\u003cp\u003eLKB1 is a tumor suppressor serine\/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552746963224,"sku":"F50223-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_079971a1-ce90-4ed3-9438-4f857eb8339a.jpg?v=1768360837","url":"https:\/\/danabiosci.com\/products\/nsj-f50223-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}