{"product_id":"nsj-f49857-0-4ml","title":"Ku70 Antibody, 0.4 ml","description":"\u003cp\u003eKu70 is a single stranded DNA-dependent ATP-dependent helicase. It has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by p70.It is involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The Ku p70\/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The Ku p70\/p86 dimer is probably involved in stabilizing broken DNA ends and bringing them together.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552769474840,"sku":"F49857-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_117075d8-6ef6-49fe-b681-189a8530c9c9.jpg?v=1768361107","url":"https:\/\/danabiosci.com\/products\/nsj-f49857-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}