{"product_id":"nsj-f48775-0-4ml","title":"Phospho-TSC2 Antibody (pS1096), 0.4 ml","description":"\u003cp\u003eIn complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Specifically stimulates the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth (By similarity).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552812859672,"sku":"F48775-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_e5df3d6b-d634-4b03-b1b2-4143c2f7c1ad.jpg?v=1768361698","url":"https:\/\/danabiosci.com\/products\/nsj-f48775-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}