{"product_id":"nsj-f48459-0-05ml","title":"Phospho-Syk Antibody (pY525\/526), 0.05 ml","description":"\u003cp\u003eSyk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.05 ml","offer_id":51552828883224,"sku":"F48459-0.05ML","price":205.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_206aa2d7-e381-4f62-abd4-6cbcd195c587.jpg?v=1768362051","url":"https:\/\/danabiosci.com\/products\/nsj-f48459-0-05ml","provider":"Dana Bioscience","version":"1.0","type":"link"}