{"product_id":"nsj-f47446-0-4ml","title":"FADD Antibody, 0.4 ml","description":"\u003cp\u003eThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6\/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10\/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552865354008,"sku":"F47446-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_e8fc232d-3684-45f8-a639-c70c022d97ae.jpg?v=1768362651","url":"https:\/\/danabiosci.com\/products\/nsj-f47446-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}