{"product_id":"nsj-f44087-0-4ml","title":"Akt1 Antibody, 0.4 ml","description":"\u003cp\u003eThis gene encodes the founding member of the Akt serine-threonine protein kinase gene family that also includes Akt2 and Akt3. This kinase is a major downstream effector of the phosphatidylinositol 3-kinase (PI3K) pathway that mediates the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). It is activated through recruitment to cellular membranes by PI3K lipid products and by phosphorylation by 3-phosphoinositide dependent kinase-1. It then further phosphorylates different downstream proteins in response to various extracellular signals and thus plays a pivotal role in mediating a variety of cellular processes, such as glucose metabolism, glycogen biosynthesis, protein synthesis and turn over, inflammatory response, cell survival (anti-apoptosis) and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51552972079384,"sku":"F44087-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_ea77ed44-d5e0-4803-b5c4-d1a30701e4cd.jpg?v=1768363517","url":"https:\/\/danabiosci.com\/products\/nsj-f44087-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}