{"product_id":"nsj-f41459-0-4ml","title":"SP1 Antibody, 0.4 ml","description":"\u003cp\u003eTranscription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4\/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":51553035059480,"sku":"F41459-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_879530ae-5112-40a7-93db-b199a34bfacf.jpg?v=1768364446","url":"https:\/\/danabiosci.com\/products\/nsj-f41459-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}