{"product_id":"new-product-701673","title":"IDH2 Rabbit mAb","description":"\u003cp\u003eIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577291256088,"sku":"A11270","price":368.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/new-product-701673","provider":"Dana Bioscience","version":"1.0","type":"link"}