{"product_id":"new-product-701524","title":"UBE2D2 Rabbit pAb","description":"\u003cp\u003eRegulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577118339352,"sku":"A10818","price":298.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A10818_1.jpg?v=1717032467","url":"https:\/\/danabiosci.com\/products\/new-product-701524","provider":"Dana Bioscience","version":"1.0","type":"link"}