{"product_id":"new-product-701416","title":"Legumain (LGMN) Rabbit pAb","description":"\u003cp\u003eThis gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal\/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577094025496,"sku":"A10570","price":298.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/new-product-701416","provider":"Dana Bioscience","version":"1.0","type":"link"}