{"product_id":"new-product-701373","title":"Siglec-8 Rabbit pAb","description":"\u003cp\u003eSialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577079902488,"sku":"A10514","price":298.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A10514_1.jpg?v=1717031694","url":"https:\/\/danabiosci.com\/products\/new-product-701373","provider":"Dana Bioscience","version":"1.0","type":"link"}