{"product_id":"new-product-701362","title":"FZD6 Rabbit pAb","description":"\u003cp\u003eThis gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt\/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577078559000,"sku":"A10503","price":298.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A10503_1.jpg?v=1717031662","url":"https:\/\/danabiosci.com\/products\/new-product-701362","provider":"Dana Bioscience","version":"1.0","type":"link"}