{"product_id":"new-product-701353","title":"RASGRP1 Rabbit pAb","description":"\u003cp\u003eThis gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk\/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48577076199704,"sku":"A10495","price":298.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/new-product-701353","provider":"Dana Bioscience","version":"1.0","type":"link"}