{"product_id":"new-product-701041","title":"TPMT Rabbit pAb","description":"\u003cp\u003eThis gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48576964624664,"sku":"A1017","price":298.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A1017_1.jpg?v=1717029775","url":"https:\/\/danabiosci.com\/products\/new-product-701041","provider":"Dana Bioscience","version":"1.0","type":"link"}