{"product_id":"new-product-700840","title":"HLA-DMB Rabbit mAb","description":"\u003cp\u003eHLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48576903774488,"sku":"A0948","price":368.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A0948_1.jpg?v=1717028733","url":"https:\/\/danabiosci.com\/products\/new-product-700840","provider":"Dana Bioscience","version":"1.0","type":"link"}