{"product_id":"new-product-700766","title":"ErbB4\/HER4 Rabbit pAb","description":"\u003cp\u003eThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48576864715032,"sku":"A0749","price":298.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/A0749_1.jpg?v=1717028328","url":"https:\/\/danabiosci.com\/products\/new-product-700766","provider":"Dana Bioscience","version":"1.0","type":"link"}