{"product_id":"new-product-700424","title":"B-Raf Rabbit pAb","description":"\u003cp\u003eThis gene encodes a protein belonging to the RAF family of serine\/threonine protein kinases. This protein plays a role in regulating the MAP kinase\/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":48576717488408,"sku":"A0038","price":298.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/new-product-700424","provider":"Dana Bioscience","version":"1.0","type":"link"}