Cloud-clone
SKU:PAB301Ge01
Polyclonal Antibody to Asymmetrical Dimethylarginine (ADMA)
Polyclonal Antibody to Asymmetrical Dimethylarginine (ADMA)
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Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
PAB301Ge01
Organism Species
Pan-species (General).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
CPB301Ge11-BSA Conjugated Asymmetrical Dimethylarginine (ADMA)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.45mg/ml
Organism Species More
Pan-species (General)
Applications
ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against ADMA. It has been selected for its ability to recognize ADMA in immunohistochemical staining and western blotting.
USAGE
Enzyme-Linked Immune Sorbent Assay: 200ng/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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PLoS One. |
Interactions among Vascular-Tone Modulators Contribute to High Altitude Pulmonary Edema and Augmented Vasoreactivity in Highlanders PubMed: PMC3439466 |
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Cytokine |
Effect of CCL5 on dimethylarginine dimethylaminohydrolase-1 production in vascular smooth muscle cells from spontaneously hypertensive rats. Pubmed: 23834755 |
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Neurol Res. |
Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats. Pubmed:25475507 |
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Int J Clin Exp Med. |
Correlation research on ADMA plasma levels and left ventricular function of peritoneal dialysis patients Pubmed:25550968 |
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Clin Respir J |
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD PubMed: 26076870 |
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Cytokine |
Dimethylarginine dimethylaminohydrolase-1 mediates inhibitory effect of interleukin-10 on angiotensin II-induced hypertensive effects in vascular smooth muscle cells of spontaneously hypertensive rats PubMed: 26375520 |
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Neurological Research |
Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats PubMed: 25475507 |
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Scientific Reports |
Dimethylarginine Dimethylaminohydrolase 2 (DDAH 2) Gene Polymorphism, Asymmetric Dimethylarginine (ADMA) Concentrations, and Risk of Coronary Artery Disease: A Case-Control Study pubmed:27677852 |
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clinica chimica acta |
Increased serum concentrations of asymmetric dimethylarginine (ADMA) in patients with early-onset coronary artery disease. pubmed:27884754 |
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The Journal of Physiology |
Asymmetric dimethylarginine (ADMA) elevation and arginase up-regulation contribute toendothelial dysfunction related to insulin resistance in rats and morbidly obese humans. pubmed:26840628 |
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Angiogenesis |
Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA). pubmed:29150732 |
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Scientific Reports |
A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling Pubmed:29523851 |
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Mechanisms of Ageing and Development |
Multivessel analysis of progressive vascular aging in the rat: Asynchronous vulnerability among vascular territories Pubmed:29605639 |
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Nutrition, Metabolism and Cardiovascular Diseases |
Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns Doi: 10.1016/j.numecd.2018.09.002 |
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Biochemical and Biophysical Research Communications |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1/DDAH/PPAR-γ/eNOS pathways in streptozotocin-induced diabetic rats Pubmed: 30454888 |
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Brazilian Journal of Pharmaceutical Science |
Demographic, clinical and lifestyle predictors for severity of erectile dysfunction and biomarkers level in Malaysian patients |
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ACS Combinatorial Science |
Novel cellularly active inhibitor regresses DDAH1 induced prostate tumor growth by restraining tumor angiogenesis through targeting DDAH1/ADMA/NOS pathway Pubmed: 30673277 |
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International Journal of the Cardiovascular Academy |
Nebivolol prevents the increase of asymmetric dimethylarginine and oxidants in hyperhomocysteinemic rats |
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Oxid Med Cell Longev |
The Role of Reactive Oxygen Species and Nitric Oxide in the Inhibition of Trichophyton rubrum Growth by HaCaT Cells Pubmed: 32104540 |
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Molecular Medicine Reports |
Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in … Pubmed: 31746378 |
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International Journal of Nephrology |
Effect of a Supervised Peridialytic Exercise Program on Serum Asymmetric Dimethylarginine in Maintenance Hemodialysis Patients Pubmed: 33163233 |
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Journal of Clinical Medicine |
The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial Pubmed: 32344735 |
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Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
Levels of endothelial substances in patients with newly identified hypertension compared with healthy controls 33463628 |
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WIENER KLINISCHE WOCHENSCHRIFT |
Non-functioning adrenal incidentalomas may increase toxic metabolites 34255169 |
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pharmaceuticals |
Effect of a Low Dose of Carvedilol on Cyclophosphamide-Induced Urinary Toxicity in Rats—A Comparison with Mesna 34959638 |
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Int J Biochem Cell Biol |
HIF-1α and Nrf2 regulates hypoxia induced overexpression of DDAH1 through promoter activation in prostate cancer Pubmed:35644470 |
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Catalog No. |
Related products for research use of Pan-species (General) Organism species |
Applications (RESEARCH USE ONLY!) |
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Magnetic Luminex Assay for Antigen Detection. |
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ELISA Kit DIY Materials for Asymmetrical Dimethylarginine (ADMA) |
Main materials for "Do It (ELISA Kit) Yourself". |
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