{"product_id":"new-product-648949","title":"Monoclonal Antibody to Collagen Type IV Alpha 1 (COL4a1)","description":"\u003cp\u003eWestern blotting: 0.2-2µg\/mL;1:500-5000 \u003cbr\u003e Immunohistochemistry: 5-20µg\/mL;1:50-200 \u003cbr\u003e Immunocytochemistry: 5-20µg\/mL;1:50-200 \u003cbr\u003e Optimal working dilutions must be determined by end user.\u003c\/p\u003e\n\u003cp\u003eProduct No.\u003c\/p\u003e\n\u003cp\u003eMAA149Ra21\u003c\/p\u003e\n\u003cp\u003eOrganism Species\u003c\/p\u003e\n\u003cp\u003eRattus norvegicus (Rat).\u003c\/p\u003e\n\u003cp\u003eSource\u003c\/p\u003e\n\u003cp\u003eMonoclonal antibody preparation\u003c\/p\u003e\n\u003cp\u003eHost\u003c\/p\u003e\n\u003cp\u003eMouse\u003c\/p\u003e\n\u003cp\u003ePotency (Clone Number)\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eIg Isotype\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003ePurification\u003c\/p\u003e\n\u003cp\u003eAntigen-specific affinity chromatography followed by Protein A affinity chromatography\u003c\/p\u003e\n\u003cp\u003eLabel\u003c\/p\u003e\n\u003cp\u003eNone\u003c\/p\u003e\n\u003cp\u003eImmunogen\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eBuffer Formulation\u003c\/p\u003e\n\u003cp\u003ePBS, pH7.4, containing 0.02% NaN3, 50% glycerol.\u003c\/p\u003e\n\u003cp\u003eTraits\u003c\/p\u003e\n\u003cp\u003eLiquid\u003c\/p\u003e\n\u003cp\u003eConcentration\u003c\/p\u003e\n\u003cp\u003e1mg\/mL\u003c\/p\u003e\n\u003cp\u003eOrganism Species More\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eApplications\u003c\/p\u003e\n\u003cp\u003eWB; IHC; ICC; IP.\u003c\/p\u003e\n\u003cp\u003eIf the antibody is used in flow cytometry, please check FCM antibodies.\u003c\/p\u003e\n\u003cp\u003eUOM\u003c\/p\u003e\n\u003cp\u003e20µl 100µl 200µl 1ml 10ml\u003c\/p\u003e\n\u003ch3\u003eSPECIFITY\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe antibody is a mouse monoclonal antibody raised against COL4a1. It has been selected for its ability to recognize COL4a1 in immunohistochemical staining and western blotting.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eUSAGE\u003c\/h3\u003e\n\u003cdiv class=\"img_parent\"\u003e\n\u003cp\u003eWestern blotting: 0.2-2µg\/mL;1:500-5000\u003cbr\u003eImmunohistochemistry: 5-20µg\/mL;1:50-200\u003cbr\u003eImmunocytochemistry: 5-20µg\/mL;1:50-200\u003cbr\u003eOptimal working dilutions must be determined by end user.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTORAGE\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eStore at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTABILITY\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.\u003c\/p\u003e\n\u003cdiv class=\"product_reference\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eMagazine\u003c\/td\u003e\n\u003ctd\u003eCitations\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCancer Research\u003c\/td\u003e\n\u003ctd\u003ePeritoneal Dissemination Requires an Sp1-Dependent CXCR4\/CXCL12 Signaling Axis and Extracellular MatrixâDirected Spheroid Formation\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26744523\" target=\"_blank\"\u003ePubmed:26744523\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePLoS One\u003c\/td\u003e\n\u003ctd\u003emiR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0173918\" target=\"_blank\"\u003e10.1371\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJournal of Diabetes \u0026amp; Metabolic Disorders\u003c\/td\u003e\n\u003ctd\u003eEndothelin-1 traps potently reduce pathologic markers back to basal levels in an in vitro model of diabetes\u003ca rel=\"nofollow\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s40200-018-0360-8\" target=\"_blank\"\u003e\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eExperimental and Molecular Pathology \u003c\/td\u003e\n\u003ctd\u003eEpitope recognized by anti-glomerular basement membrane (GBM) antibody in a patient with repeated relapse of anti-GBM disease\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014480018304672\" target=\"_blank\"\u003ePubmed: 30817909\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJournal of Diabetes \u0026amp; Metabolic Disorders\u003c\/td\u003e\n\u003ctd\u003eIn vivo studies demonstrate that endothelin-1 traps are a potential therapy for type I diabetes\u003ca rel=\"nofollow\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s40200-019-00400-7\" target=\"_blank\"\u003e\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFrontiers in Endocrinology\u003c\/td\u003e\n\u003ctd\u003eCurcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31920992\/\" target=\"_blank\"\u003ePubmed: 31920992\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product_relation\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eCatalog No.\u003c\/td\u003e\n\u003ctd class=\"td_2\"\u003eRelated products for research use of Rattus norvegicus (Rat) Organism species\u003c\/td\u003e\n\u003ctd class=\"td_3\"\u003eApplications (RESEARCH USE ONLY!)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRPA149Ra01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/RPA149Ra01.html\"\u003eRecombinant Collagen Type IV Alpha 1 (COL4a1)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003ePositive Control; Immunogen; SDS-PAGE; WB.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePAA149Ra01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/PAA149Ra01.html\"\u003ePolyclonal Antibody to Collagen Type IV Alpha 1 (COL4a1)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eWB; IHC; ICC; IP.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMAA149Ra21\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/MAA149Ra21.html\"\u003eMonoclonal Antibody to Collagen Type IV Alpha 1 (COL4a1)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eWB; IHC; ICC; IP.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSEA149Ra\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/SEA149Ra.html\"\u003eELISA Kit for Collagen Type IV Alpha 1 (COL4a1)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eEnzyme-linked immunosorbent assay for Antigen Detection.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLMA149Ra\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/LMA149Ra.html\"\u003eMagnetic Luminex Assay Kit for Collagen Type IV Alpha 1 (COL4a1) ,etc.\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eMagnetic Luminex Assay for Antigen Detection.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Cloud-clone","offers":[{"title":"200µl \/ 1mg\/mL \/ Rattus norvegicus (Rat)","offer_id":47595823857944,"sku":"MAA149Ra21","price":362.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/Logo_Cloud_Clone_fb0daea9-de4b-48fa-962f-f5136be6ab88.png?v=1706328228","url":"https:\/\/danabiosci.com\/products\/new-product-648949","provider":"Dana Bioscience","version":"1.0","type":"link"}