{"product_id":"new-product-642860","title":"Polyclonal Antibody to Activated Protein C (APC)","description":"\u003cp\u003eWestern blotting: 0.2-2µg\/mL;1:250-2500 \u003cbr\u003e Immunohistochemistry: 5-20µg\/mL;1:25-100 \u003cbr\u003e Immunocytochemistry: 5-20µg\/mL;1:25-100 \u003cbr\u003e Optimal working dilutions must be determined by end user.\u003c\/p\u003e\n\u003cp\u003eProduct No.\u003c\/p\u003e\n\u003cp\u003ePAA738Ra01\u003c\/p\u003e\n\u003cp\u003eOrganism Species\u003c\/p\u003e\n\u003cp\u003eRattus norvegicus (Rat).\u003c\/p\u003e\n\u003cp\u003eSource\u003c\/p\u003e\n\u003cp\u003ePolyclonal antibody preparation\u003c\/p\u003e\n\u003cp\u003eHost\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003ePotency\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eIg Type\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003ePurification\u003c\/p\u003e\n\u003cp\u003eAntigen-specific affinity chromatography followed by Protein A affinity chromatography\u003c\/p\u003e\n\u003cp\u003eLabel\u003c\/p\u003e\n\u003cp\u003eNone\u003c\/p\u003e\n\u003cp\u003eImmunogen\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eBuffer Formulation\u003c\/p\u003e\n\u003cp\u003e0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.\u003c\/p\u003e\n\u003cp\u003eTraits\u003c\/p\u003e\n\u003cp\u003eLiquid\u003c\/p\u003e\n\u003cp\u003eConcentration\u003c\/p\u003e\n\u003cp\u003e0.5mg\/ml\u003c\/p\u003e\n\u003cp\u003eOrganism Species More\u003c\/p\u003e\n\u003cp\u003en\/a\u003c\/p\u003e\n\u003cp\u003eApplications\u003c\/p\u003e\n\u003cp\u003eWB; IHC; ICC; IP.\u003c\/p\u003e\n\u003cp\u003eIf the antibody is used in flow cytometry, please check FCM antibodies.\u003c\/p\u003e\n\u003cp\u003eUOM\u003c\/p\u003e\n\u003cp\u003e20µl 100µl 200µl 1ml 10ml\u003c\/p\u003e\n\u003ch3\u003eSPECIFITY\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe antibody is a rabbit polyclonal antibody raised against APC. It has been selected for its ability to recognize APC in immunohistochemical staining and western blotting.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eUSAGE\u003c\/h3\u003e\n\u003cdiv class=\"img_parent\"\u003e\n\u003cp\u003eWestern blotting: 0.5-2µg\/mL\u003cbr\u003eImmunohistochemistry: 5-20µg\/mL\u003cbr\u003eImmunocytochemistry: 5-20µg\/mL\u003cbr\u003eOptimal working dilutions must be determined by end user.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTORAGE\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eStore at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTABILITY\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.\u003c\/p\u003e\n\u003cdiv class=\"product_reference\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eMagazine\u003c\/td\u003e\n\u003ctd\u003eCitations\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThe Journal of Immunology\u003c\/td\u003e\n\u003ctd\u003eActivated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.jimmunol.org\/content\/187\/6\/3413.short\" target=\"_blank\"\u003eJimmunol: 3413\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCritical Care\u003c\/td\u003e\n\u003ctd\u003eDisseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.biomedcentral.com\/content\/pdf\/cc10553.pdf\" target=\"_blank\"\u003eBioMed: cc10553\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMolecular Endocrinology\u003c\/td\u003e\n\u003ctd\u003eIntraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/mend.endojournals.org\/content\/26\/2\/331.short\" target=\"_blank\"\u003eEndo: source\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eScandinavian Journal of Trauma, Resuscitation and Emergency Medicine\u003c\/td\u003e\n\u003ctd\u003eHigh levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.sjtrem.com\/content\/pdf\/1757-7241-20-27.pdf\" target=\"_blank\"\u003eSjtrem:1757-7241\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrit Care.\u003c\/td\u003e\n\u003ctd\u003eImpact of plasma histones in human sepsis and their contribution to cellular injury and inflammation\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25260379\" target=\"_blank\"\u003ePubmed:25260379\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAm J Physiol Heart Circ Physiol.\u003c\/td\u003e\n\u003ctd\u003eMonocytes regulate systemic coagulation and inflammation in abdominal sepsis\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25502108\" target=\"_blank\"\u003ePubmed:25502108\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNeuroscience\u003c\/td\u003e\n\u003ctd\u003eProtective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25936678\" target=\"_blank\"\u003ePubMed: 25936678\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJournal of Intensive Care\u003c\/td\u003e\n\u003ctd\u003eActivated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26734467\" target=\"_blank\"\u003ePubmed:26734467\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJournal of Biological Chemistry\u003c\/td\u003e\n\u003ctd\u003eBrain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells.\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.jbc.org\/content\/early\/2018\/03\/19\/jbc.RA118.002639.short\" target=\"_blank\"\u003eJBC:Source\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJ Thromb Haemost\u003c\/td\u003e\n\u003ctd\u003eA multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32480432\/\" target=\"_blank\"\u003ePubmed: 32480432\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003eValidation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34021192\" target=\"_blank\"\u003e34021192\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product_relation\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eCatalog No.\u003c\/td\u003e\n\u003ctd class=\"td_2\"\u003eRelated products for research use of Rattus norvegicus (Rat) Organism species\u003c\/td\u003e\n\u003ctd class=\"td_3\"\u003eApplications (RESEARCH USE ONLY!)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRPA738Ra01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/RPA738Ra01.html\"\u003eRecombinant Activated Protein C (APC)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003ePositive Control; Immunogen; SDS-PAGE; WB.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePAA738Ra01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/PAA738Ra01.html\"\u003ePolyclonal Antibody to Activated Protein C (APC)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eWB; IHC; ICC; IP.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSEA738Ra\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/SEA738Ra.html\"\u003eELISA Kit for Activated Protein C (APC)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eEnzyme-linked immunosorbent assay for Antigen Detection.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLMA738Ra\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/LMA738Ra.html\"\u003eMagnetic Luminex Assay Kit for Activated Protein C (APC) ,etc.\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eMagnetic Luminex Assay for Antigen Detection.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Cloud-clone","offers":[{"title":"200µl \/ 500µg\/mL \/ Rattus norvegicus (Rat)","offer_id":47594125590808,"sku":"PAA738Ra01","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/Logo_Cloud_Clone_10caf27a-d408-4610-9a34-23c6e03293f5.png?v=1706288464","url":"https:\/\/danabiosci.com\/products\/new-product-642860","provider":"Dana Bioscience","version":"1.0","type":"link"}