{"product_id":"new-product-622499","title":"Recombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A)","description":"\u003cp\u003eProkaryotic expression\u003c\/p\u003e\n\u003cp\u003eProduct No.\u003c\/p\u003e\n\u003cp\u003eRPP155Bo01\u003c\/p\u003e\n\u003cp\u003eOrganism Species\u003c\/p\u003e\n\u003cp\u003eBos taurus; Bovine (Cattle).\u003c\/p\u003e\n\u003cp\u003eSource\u003c\/p\u003e\n\u003cp\u003eProkaryotic expression\u003c\/p\u003e\n\u003cp\u003eHost\u003c\/p\u003e\n\u003cp\u003eE.coli\u003c\/p\u003e\n\u003cp\u003eEndotoxin Level\u003c\/p\u003e\n\u003cp\u003e\u0026lt;1.0EU per 1µg (determined by the LAL method)\u003c\/p\u003e\n\u003cp\u003eSubcellular Location\u003c\/p\u003e\n\u003cp\u003eSecreted\u003c\/p\u003e\n\u003cp\u003ePredicted Molecular Mass\u003c\/p\u003e\n\u003cp\u003e37.2kDa\u003c\/p\u003e\n\u003cp\u003eAccurate Molecular Mass\u003c\/p\u003e\n\u003cp\u003e40kDa(Analysis of differences refer to the manual)\u003c\/p\u003e\n\u003cp\u003eResidues \u0026amp; Tags\u003c\/p\u003e\n\u003cp\u003eMet1~Phe284 with N-terminal His Tag\u003c\/p\u003e\n\u003cp\u003eBuffer Formulation\u003c\/p\u003e\n\u003cp\u003e20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.\u003c\/p\u003e\n\u003cp\u003eTraits\u003c\/p\u003e\n\u003cp\u003eFreeze-dried powder\u003c\/p\u003e\n\u003cp\u003ePurity\u003c\/p\u003e\n\u003cp\u003e\u0026gt; 97%\u003c\/p\u003e\n\u003cp\u003eIsoelectric Point\u003c\/p\u003e\n\u003cp\u003e8.1\u003c\/p\u003e\n\u003cp\u003eApplications\u003c\/p\u003e\n\u003cp\u003ePositive Control; Immunogen; SDS-PAGE; WB.\u003c\/p\u003e\n\u003cp\u003eIf bio-activity of the protein is needed, please check active protein.\u003c\/p\u003e\n\u003cp\u003eUOM\u003c\/p\u003e\n\u003cp\u003e10µg 50µg 200µg 1mg 5mg\u003c\/p\u003e\n\u003ch3\u003eSEQUENCE\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"product_image\"\u003e\n\u003cimg src=\"https:\/\/www.cloud-clone.com\/upload\/product\/pictures\/RPP155Bo01-202008261721158291.png\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eUSAGE\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eReconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg\/mL. Do not vortex.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTORAGE\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eAvoid repeated freeze\/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSTABILITY\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.\u003c\/p\u003e\n\u003cdiv class=\"product_reference\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eMagazine\u003c\/td\u003e\n\u003ctd\u003eCitations\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMedical Oncology\u003c\/td\u003e\n\u003ctd\u003eWls promotes the proliferation of breast cancer cells via Wnt signaling\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25801232\" target=\"_blank\"\u003ePubmed:25801232\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJ Histochem Cytochem\u003c\/td\u003e\n\u003ctd\u003eWnt3a Mediates the Inhibitory Effect of Hyperoxia on the Transdifferentiation of AECIIs to AECIs\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26209081\" target=\"_blank\"\u003ePubMed: 26209081\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePloS one\u003c\/td\u003e\n\u003ctd\u003eGelatin device for the delivery of growth factors involved in endochondral ossification\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28380024\" target=\"_blank\"\u003epubmed:28380024\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLife Sciences\u003c\/td\u003e\n\u003ctd\u003eHepatoprotective effect of hesperidin in hepatocellular carcinoma: Involvement of Wnt signaling pathways.\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28754618\" target=\"_blank\"\u003epubmed:28754618\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOxidative Medicine and Cellular Longevity\u003c\/td\u003e\n\u003ctd\u003eSecreted Frizzled-Related Protein-2 Inhibits Doxorubicin Induced Apoptosis Mediated Through the Akt-mTOR Pathway in Soleus Muscle\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30151071\" target=\"_blank\"\u003ePubmed:30151071\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThe Showa University Journal of Medical Sciences\u003c\/td\u003e\n\u003ctd\u003eEribulin Treatment Induces High Expression of miR-195 and Inactivates the Wnt\/β-catenin Signaling Pathway in Triple-negative Breast Cancer\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/sujms\/30\/3\/30_359\/_article\/-char\/ja\/\" target=\"_blank\"\u003eDoi: 10.15369\/sujms.30.359\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eJournal of Cancer\u003c\/td\u003e\n\u003ctd\u003eOncogenic Wnt3a: A Candidate Specific Marker and Novel Molecular Target for Hepatocellular Carcinoma\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31737122\/\" target=\"_blank\"\u003ePubmed: 31737122\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCANCER LETTERS\u003c\/td\u003e\n\u003ctd\u003eKnock down of BMSC-derived Wnt3a or its antagonist analogs attenuate colorectal carcinogenesis induced by chronic Fusobacterium nucleatum infection\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32920199\/\" target=\"_blank\"\u003ePubmed: 32920199\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiomaterials\u003c\/td\u003e\n\u003ctd\u003eAn improved osseointegration of metal implants by pitavastatin loaded multilayer films with osteogenic and angiogenic properties\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"nofollow\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34823885\/\" target=\"_blank\"\u003e34823885\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product_relation\"\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr class=\"first_tr\"\u003e\n\u003ctd class=\"td_1\"\u003eCatalog No.\u003c\/td\u003e\n\u003ctd class=\"td_2\"\u003eRelated products for research use of Bos taurus; Bovine (Cattle) Organism species\u003c\/td\u003e\n\u003ctd class=\"td_3\"\u003eApplications (RESEARCH USE ONLY!)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRPP155Bo01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/RPP155Bo01.html\"\u003eRecombinant Wingless Type MMTV Integration Site Family, Member 3A (WNT3A)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003ePositive Control; Immunogen; SDS-PAGE; WB.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePAP155Bo01\u003c\/td\u003e\n\u003ctd\u003e\u003ca href=\"https:\/\/www.cloud-clone.com\/products\/PAP155Bo01.html\"\u003ePolyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3A (WNT3A)\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd\u003eWB; IHC; ICC; IP.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Cloud-clone","offers":[{"title":"50ug \/ \u003e 97% \/ Bos taurus; Bovine (Cattle)","offer_id":47569634099480,"sku":"RPP155Bo01","price":518.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/NP_41afcbf7-fc42-4a8e-a91b-f11a0bc383a3.jpg?v=1705992381","url":"https:\/\/danabiosci.com\/products\/new-product-622499","provider":"Dana Bioscience","version":"1.0","type":"link"}