{"product_id":"new-product-609698","title":"anti- AKR1C3 antibody","description":"\u003cp\u003eDelve into the complex world of steroid hormone metabolism and aldo-keto reductases with our state-of-the-art Anti-AKR1C3 Antibody, now available in a convenient 100µg size.\u003cbr\u003e\u003cbr\u003eThe Anti-AKR1C3 Antibody, also known as Aldo-Keto Reductase Family 1 Member C3, is meticulously designed to meet the exacting standards of the scientific community. AKR1C3 plays a crucial role in the biosynthesis and metabolism of steroid hormones, making it a central focus in endocrinology and cancer research. Our antibody offers exceptional specificity and sensitivity, making it an ideal choice for applications such as enzyme assays, hormone metabolism studies, and more.\u003cbr\u003e\u003cbr\u003eWhat truly distinguishes our Anti-AKR1C3 Antibody is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.\u003cbr\u003e\u003cbr\u003eWith a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.\u003cbr\u003e\u003cbr\u003eEngineered for user-friendliness, our Anti-AKR1C3 Antibody is suitable for researchers at all levels, from newcomers to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.\u003cbr\u003e\u003cbr\u003eEmpower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AKR1C3 Antibody at your disposal. Step into the forefront of scientific discovery in steroid hormone metabolism and hormone-related diseases with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AKR1C3's roles in hormone biosynthesis and cancer progression.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAKR1C3 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis gene encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and\/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ealdo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e17 beta HSD 5, 3 alpha HSD type 2, 3 alpha HSD type II, brain, AKR1C3, DD 3, DD3, DDX, Dihydrodiol dehydrogenase 3, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, Prostaglandin F synthase\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e37 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB, IHC, IF\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P42330\"\u003eP42330\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content-area w-full py-4 lg:w-3\/4 lg:pr-4 lg:py-12\" id=\"primary\"\u003e\u003cmain class=\"site-main\" id=\"main\"\u003e\n\u003carticle class=\"post-12225 ft_product type-ft_product status-publish hentry product_host-rabbit product_clonality-polyclonal product_reactivity-human product_reactivity-rat product_tested_application-elisa product_tested_application-if product_tested_application-ihc product_tested_application-wb ft_product_category-primary-antibody ft_research_area-metabolism\" id=\"post-12225\"\u003e\n\u003cdiv class=\"entry-details\"\u003e\n\u003cdiv class=\"product-tab-slider w-full mt-6\"\u003e\n\u003cdiv class=\"product-tab-slider--container\"\u003e\n\u003cdiv class=\"product-tab-slider--body\" id=\"specifications\"\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdd class=\"one-column flex flex-wrap\"\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab00262.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eImmunohistochemistry of paraffin-embedded rat heart using FNab00262(AKR1C3 antibody) at dilution of 1:100\u003c\/div\u003e\n\u003c\/dd\u003e\n\u003cdd class=\"one-column flex flex-wrap\"\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab00262.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eHepG2 cells were subjected to SDS PAGE followed by western blot with FNab00262(AKR1C3 antibody) at dilution of 1:1000\u003c\/div\u003e\n\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cfooter class=\"entry-footer my-2\"\u003e\u003c\/footer\u003e\u003c\/article\u003e\n\u003c\/main\u003e\u003c\/div\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562482417944,"sku":"FNab00262","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_6c9bae31-6dfe-40e2-b761-224068e74b6f.jpg?v=1705901322","url":"https:\/\/danabiosci.com\/products\/new-product-609698","provider":"Dana Bioscience","version":"1.0","type":"link"}