{"product_id":"new-product-609484","title":"anti- APH1A antibody","description":"\u003cp\u003eUnlock the mysteries of cellular signaling and Alzheimer's disease with our Anti-APH1A Antibody. APH1A, or Anterior Pharynx Defective 1 Homolog A, is a pivotal component of the γ-secretase complex, a molecular machine crucial for the processing of amyloid precursor protein and the generation of amyloid-beta peptides implicated in Alzheimer's disease. Our meticulously crafted antibody, available in a 100µg size, provides exceptional specificity and sensitivity, ensuring the precision and reliability required for your research endeavors.\u003cbr\u003e\u003cbr\u003eWith 100µg of this high-quality antibody at your disposal, you have the flexibility to conduct a wide range of experiments. Whether you're exploring APH1A's roles in amyloid-beta production, investigating its interactions within the γ-secretase complex, or diving into its implications in neurodegenerative diseases, this antibody empowers you with the precision needed for impactful scientific discoveries.\u003cbr\u003e\u003cbr\u003eOur Anti-APH1A Antibody has undergone rigorous validation to ensure its reliability and reproducibility. Trust in the consistency of your results, enabling you to draw accurate conclusions and make significant strides in your research endeavors, particularly in the field of Alzheimer's disease and neurodegeneration.\u003cbr\u003e\u003cbr\u003eUnlock the secrets of Alzheimer's disease and cellular signaling with confidence. Whether you are an experienced neuroscientist or just embarking on your scientific journey, our Anti-APH1A Antibody promises to be an invaluable asset in your laboratory, driving your research forward as you seek to unravel the complexities of this devastating disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAPH1A antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP(beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eanterior pharynx defective 1 homolog A\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAPH 1A, Aph 1alpha, APH1A, CGI 78, Gamma secretase subunit APH 1A, PSF, UNQ579\/PRO1141\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e30 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:500 - 1:1000\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q96BI3\"\u003eQ96BI3\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab00481.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eHeLa cells were subjected to SDS PAGE followed by western blot with FNab00481(APH1A antibody) at dilution of 1:500\u003c\/div\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562426253592,"sku":"FNab00481","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_e5456753-d844-456e-b552-e4946e948b0c.jpg?v=1705900485","url":"https:\/\/danabiosci.com\/products\/new-product-609484","provider":"Dana Bioscience","version":"1.0","type":"link"}