{"product_id":"new-product-608561","title":"anti- CD1A antibody","description":"\u003cp\u003eUnlock the secrets of antigen presentation with our Anti-CD1A Antibody, now available in a 100µg size. CD1A is a member of the CD1 family of transmembrane glycoproteins, primarily expressed on dendritic cells and other antigen-presenting cells. It plays a pivotal role in presenting lipid antigens to T cells, bridging innate and adaptive immune responses.\u003cbr\u003e\u003cbr\u003eOur meticulously developed monoclonal antibody ensures exceptional specificity and sensitivity, making it the ideal choice for various applications, including flow cytometry, immunohistochemistry, and functional studies. It provides the precision and reliability needed for accurate results in your CD1A-related research.\u003cbr\u003e\u003cbr\u003eWith 100µg at your disposal, you have a substantial supply for multiple experiments, ensuring the continuity of your research without frequent reordering.\u003cbr\u003e\u003cbr\u003eDelve into the intricate world of antigen presentation with our Anti-CD1A Antibody and uncover the mechanisms underlying immune responses to lipid antigens.\u003c\/p\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdt\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCD22 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eProtein A+G purification\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMouse\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003emonoclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG1\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCD22 molecule\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB cell receptor CD22, BL CAM, CD22, CD22 molecule, SIGLEC 2, SIGLEC2, T cell surface antigen Leu 14\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e135 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB, IHC\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB : 1:1000-1:10000\u003cbr\u003e IHC : 1:200-1:800\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P20273\"\u003eP20273\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab01435.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eJurkat cells were subjected to SDS PAGE followed by western blot with FNab01435 (CD1A antibody) at dilution of 1:2000\u003c\/div\u003e\n\u003c\/dt\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\n\u003cdiv id=\"primary\" class=\"content-area w-full py-4 lg:w-3\/4 lg:pr-4 lg:py-12\" data-mce-fragment=\"1\"\u003e\u003cmain id=\"main\" class=\"site-main\" data-mce-fragment=\"1\"\u003e\n\u003carticle id=\"post-14512\" class=\"post-14512 ft_product type-ft_product status-publish hentry product_host-mouse product_clonality-monoclonal product_reactivity-human product_tested_application-elisa product_tested_application-wb ft_product_category-primary-antibody ft_research_area-immunology ft_research_area-tumor\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"entry-details\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"product-tab-slider w-full mt-6\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"product-tab-slider--container\" data-mce-fragment=\"1\"\u003e\n\u003cdiv id=\"specifications\" class=\"product-tab-slider--body\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"content-block\" data-mce-fragment=\"1\"\u003e\n\u003cdl class=\"content-block--list\" data-mce-fragment=\"1\"\u003e\n\u003cdd class=\"one-column flex flex-wrap\" data-mce-fragment=\"1\"\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\" data-mce-fragment=\"1\"\u003e\u003c\/figure\u003e\n\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/article\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562240819480,"sku":"FNab01435","price":310.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_64b84e70-aa7d-48a1-96f4-a65afb1ec63e.jpg?v=1705896817","url":"https:\/\/danabiosci.com\/products\/new-product-608561","provider":"Dana Bioscience","version":"1.0","type":"link"}