{"product_id":"new-product-608259","title":"anti- Claudin 4-specific antibody","description":"\u003cp\u003eDelve into the intricate world of tight junctions and epithelial barrier function with our Anti-Claudin 4-Specific Antibody, now available in a 100µg size. Claudin 4 is a critical component of tight junctions in epithelial cells, contributing to the formation and maintenance of epithelial barriers.\u003cbr\u003e\u003cbr\u003eThis meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of Claudin 4 protein in your experiments. Researchers studying epithelial biology, barrier function, or related areas will benefit from the accuracy and reliability of this antibody.\u003cbr\u003e\u003cbr\u003eOur high-quality Anti-Claudin 4-Specific Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of epithelial barrier research and gain valuable insights into the role of Claudin 4 in regulating epithelial permeability and barrier integrity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eClaudin 4-specific antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eClaudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small(20-27 kDa) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. This antibody is specifically against claudin 4.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eclaudin 4\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eclaudin 4, CLDN4, CPE R, CPE receptor, CPER, CPETR, CPETR1, hCPE R, WBSCR8\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e22 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB, IHC, IP\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/O14493\"\u003eO14493\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab01739.jpg\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01739(Claudin 4-specific Antibody) at dilution of 1:50\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image3\/FNab01739.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003eIP Result of anti-Claudin 4-specific (IP:FNab01739, 4ug; Detection:FNab01739 1:300) with human placenta tissue lysate 4400ug.\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab01739.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003emouse small intestine tissue were subjected to SDS PAGE followed by western blot with FNab01739(CLDN4-specific antibody) at dilution of 1:500\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562180821272,"sku":"FNab01739","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_01aee306-3596-4db9-a43f-c266c38ee822.jpg?v=1705895564","url":"https:\/\/danabiosci.com\/products\/new-product-608259","provider":"Dana Bioscience","version":"1.0","type":"link"}