{"product_id":"new-product-608144","title":"anti- Connexin-43 antibody","description":"\u003cp\u003eStep into the world of intercellular communication and cardiac function with our Anti-Connexin-43 Antibody, meticulously developed and conveniently available in a 100µg size. Connexin-43, a major constituent of gap junctions in the heart, plays a pivotal role in synchronizing electrical impulses between cardiomyocytes and ensuring proper cardiac function. This high-quality polyclonal antibody serves as your essential tool for investigating the intricate processes of cardiac conduction and its implications in heart health.\u003cbr\u003e\u003cbr\u003eOur polyclonal antibody is thoughtfully designed and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're exploring cardiac arrhythmias, heart development, or the role of Connexin-43 in cardiac diseases, this antibody is your trusted research partner.\u003cbr\u003e\u003cbr\u003eThe 100µg size offers a generous supply of antibody to support your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-Connexin-43 Antibody to advance your scientific exploration of intercellular communication in the heart and contribute to a deeper understanding of cardiac physiology.\u003cbr\u003e\u003cbr\u003eUnraveling the intricacies of Connexin-43's role in cardiac conduction and its impact on heart health is essential for deciphering the complexities of cardiovascular diseases and their implications for patient care. Our polyclonal antibody empowers you to delve into this intriguing area of research, potentially paving the way for novel therapeutic strategies and improved cardiac treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eConnexin-43 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003egap junction protein, alpha 1, 43kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eConnexin-43, CX43, DFNB38, Gap junction alpha 1 protein, GJA1, GJAL, ODDD\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e47 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB, IHC, FC, IP\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:500\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P17302\"\u003eP17302\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab01861.jpg\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunohistochemistry of paraffin-embedded mouse heart using FNab01861(GJA1 antibody) at dilution of 1:100\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image2\/FNab01861.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003eImmunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using FNab01861 at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image3\/FNab01861.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003eIP Result of anti-Connexin-43 (IP: FNab01861, 4ug; Detection: FNab01861 1:1000) with mouse heart tissue lysate 3200ug.\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab01861.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003eHeLa cells were subjected to SDS PAGE followed by western blot with FNab01861(GJA1 antibody) at dilution of 1:1000\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562160177432,"sku":"FNab01861","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_c30ac0cf-d12a-4039-b33f-d0ae4a2dab9e.jpg?v=1705895096","url":"https:\/\/danabiosci.com\/products\/new-product-608144","provider":"Dana Bioscience","version":"1.0","type":"link"}