{"product_id":"new-product-607906","title":"anti- CXCR4 antibody","description":"\u003cp\u003eOur Anti-CXCR4 Polyclonal Antibody, available in a 100µg size, is a versatile and essential tool for researchers exploring the intricate roles of CXCR4, a chemokine receptor, in immune cell migration, hematopoiesis, and cancer metastasis.\u003cbr\u003e\u003cbr\u003eAs a polyclonal antibody, it offers enhanced sensitivity and versatility, enabling you to delve deep into the molecular mechanisms underlying chemokine receptor signaling. We have rigorously validated the specificity of this antibody to ensure precise and reproducible results in your experiments.\u003cbr\u003e\u003cbr\u003eIts compact size allows for a wide range of applications, from immunoprecipitation to flow cytometry. Whether you're unraveling the secrets of chemokine receptor function or exploring therapeutic targets, our Anti-CXCR4 Polyclonal Antibody is a trusted resource that will advance your scientific investigations. Trust in its quality to propel your research forward.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCXCR4 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003echemokine (C-X-C motif) receptor 4\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e60 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, IHC, WB\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:500 - 1:2000; IHC: 1:50 - 1:200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P61073\"\u003eP61073\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content-area w-full py-4 lg:w-3\/4 lg:pr-4 lg:py-12\" id=\"primary\"\u003e\u003cmain class=\"site-main\" id=\"main\"\u003e\n\u003carticle class=\"post-12418 ft_product type-ft_product status-publish hentry product_host-rabbit product_clonality-polyclonal product_reactivity-human product_reactivity-mouse product_reactivity-rat product_tested_application-elisa product_tested_application-ihc product_tested_application-wb ft_product_category-primary-antibody ft_research_area-developmental-biology ft_research_area-immunology ft_research_area-neuroscience ft_research_area-signal-transduction ft_research_area-stem-cells\" id=\"post-12418\"\u003e\n\u003cdiv class=\"entry-details\"\u003e\n\u003cdiv class=\"product-tab-slider w-full mt-6\"\u003e\n\u003cdiv class=\"product-tab-slider--container\"\u003e\n\u003cdiv class=\"product-tab-slider--body\" id=\"specifications\"\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdt\u003eProduct Name\u003c\/dt\u003e\n\u003cdd\u003eCXCR4 antibody\u003c\/dd\u003e\n\u003cdt\u003eCatalogue No.\u003c\/dt\u003e\n\u003cdd\u003eFNab02102\u003c\/dd\u003e\n\u003cdt\u003eSize\u003c\/dt\u003e\n\u003cdd\u003e100µg\u003c\/dd\u003e\n\u003cdt\u003eForm\u003c\/dt\u003e\n\u003cdd\u003eliquid\u003c\/dd\u003e\n\u003cdt\u003ePurification\u003c\/dt\u003e\n\u003cdd\u003eImmunogen affinity purified\u003c\/dd\u003e\n\u003cdt\u003ePurity\u003c\/dt\u003e\n\u003cdd\u003e≥95% as determined by SDS-PAGE\u003c\/dd\u003e\n\u003cdt\u003eHost\u003c\/dt\u003e\n\u003cdd\u003eRabbit\u003c\/dd\u003e\n\u003cdt\u003eClonality\u003c\/dt\u003e\n\u003cdd\u003epolyclonal\u003c\/dd\u003e\n\u003cdt\u003eIsotype\u003c\/dt\u003e\n\u003cdd\u003eIgG\u003c\/dd\u003e\n\u003cdt\u003eStorage\u003c\/dt\u003e\n\u003cdd\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003eBACKGROUND\u003c\/span\u003e\u003c\/div\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdd class=\"one-column\"\u003eThis gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003eIMMUNOGEN INFORMATION\u003c\/span\u003e\u003c\/div\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdt\u003eImmunogen\u003c\/dt\u003e\n\u003cdd\u003echemokine (C-X-C motif) receptor 4\u003c\/dd\u003e\n\u003cdt\u003eSynonyms\u003c\/dt\u003e\n\u003cdd\u003eCD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM\u003c\/dd\u003e\n\u003cdt\u003eObserved MW\u003c\/dt\u003e\n\u003cdd\u003e60 kDa\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003eAPPLICATION\u003c\/span\u003e\u003c\/div\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdt\u003eTested Application\u003c\/dt\u003e\n\u003cdd\u003eELISA, IHC, WB\u003c\/dd\u003e\n\u003cdt\u003eRecommended Dilution\u003c\/dt\u003e\n\u003cdd\u003eWB: 1:500 - 1:2000; IHC: 1:50 - 1:200\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003eUNIPROT INFORMATION\u003c\/span\u003e\u003c\/div\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdt\u003eUniProt ID\u003c\/dt\u003e\n\u003cdd\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P61073\"\u003eP61073\u003c\/a\u003e\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content-block\"\u003e\n\u003cdiv class=\"content-block--tag\"\u003e\u003cspan\u003eIMAGES\u003c\/span\u003e\u003c\/div\u003e\n\u003cdl class=\"content-block--list\"\u003e\n\u003cdd class=\"one-column flex flex-wrap\"\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab02102.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eImmunohistochemistry of paraffin-embedded rat brain using FNab02102(CXCR4 antibody) at dilution of 1:100\u003c\/div\u003e\n\u003c\/dd\u003e\n\u003cdd class=\"one-column flex flex-wrap\"\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab02102.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003erat spleen tissue were subjected to SDS PAGE followed by western blot with FNab02102( CXCR4 Antibody) at dilution of 1:1000\u003c\/div\u003e\n\u003c\/dd\u003e\n\u003c\/dl\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cfooter class=\"entry-footer my-2\"\u003e\u003c\/footer\u003e\u003c\/article\u003e\n\u003c\/main\u003e\u003c\/div\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562095198488,"sku":"FNab02102","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_7bf0f0ad-a7a6-4744-a0a1-441c5a95be66.jpg?v=1705894100","url":"https:\/\/danabiosci.com\/products\/new-product-607906","provider":"Dana Bioscience","version":"1.0","type":"link"}