{"product_id":"new-product-607835","title":"anti- CYP4F8 antibody","description":"\u003cp\u003eOur Anti-CYP4F8 Antibody, available in a 100µg size, is a crucial tool for researchers studying the cytochrome P450 enzyme CYP4F8, known for its role in the metabolism of arachidonic acid and the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE).\u003cbr\u003e\u003cbr\u003eCYP4F8 is involved in the conversion of arachidonic acid to 20-HETE, a bioactive lipid with diverse physiological functions, including the regulation of blood pressure, vascular tone, and kidney function. Understanding the functions and regulation of CYP4F8 is essential for unraveling its contributions to lipid signaling pathways and its implications in cardiovascular and renal physiology.\u003cbr\u003e\u003cbr\u003eOur antibody has undergone rigorous validation for specificity and sensitivity, ensuring precise and reproducible results in your experiments. Its compact size allows for versatility in applications, whether you're conducting lipid metabolism studies, investigating vascular regulation, or exploring therapeutic targets. Trust in the quality of our Anti-CYP4F8 Antibody to accelerate your scientific investigations and contribute to advancements in cardiovascular and renal research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCYP4F8 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHydroxylates arachidonic acid(20:4n-6) to(18R)-hydroxyarachidonate. Shows little activity against prostaglandin(PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid(22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid(22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid(22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ecytochrome P450, family 4, subfamily F, polypeptide 8\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, IHC\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIHC: 1:20-1:200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P98187\"\u003eP98187\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab02174.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eImmunohistochemistry of paraffin-embedded human skin tissue slide using FNab02174(CYP4F8 Antibody) at dilution of 1:50\u003c\/div\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47562070720792,"sku":"FNab02174","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_ecbc60c5-590c-4967-a2ab-f32d94224b11.jpg?v=1705893811","url":"https:\/\/danabiosci.com\/products\/new-product-607835","provider":"Dana Bioscience","version":"1.0","type":"link"}