{"product_id":"new-product-602237","title":"anti- SIX1 antibody","description":"\u003cp\u003eanti- SIX1 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduct Name\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSIX1 antibody\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e100µg\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eliquid\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eImmunogen affinity purified\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e≥95% as determined by SDS-PAGE\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRabbit\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003epolyclonal\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIgG\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBACKGROUND\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTranscription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2(By similarity). Regulates the expression of CCNA1.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMMUNOGEN INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSIX homeobox 1\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBOS3, DFNA23, Homeobox protein SIX1, Sine oculis homeobox homolog 1, SIX homeobox 1, SIX1, TIP39\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e32-35 kDa\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAPPLICATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eELISA, WB, IF, IP\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRecommended Dilution\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUNIPROT INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q15475\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eQ15475\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMAGES\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image3\/FNab07886.jpg\" style=\"font-size: 0.875rem;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIP Result of anti-SIX1 (IP:FNab07886, 3ug; Detection:FNab07886 1:1000) with HEK-293 cells lysate 2560ug.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab07886.jpg\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA2780 cells were subjected to SDS PAGE followed by western blot with FNab07886(SIX1 antibody) at dilution of 1:800\u003c\/span\u003e\u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":47560998387992,"sku":"FNab07886","price":310.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_52bbb52e-7064-4f6b-a983-fa6d2a7483f2.jpg?v=1705870420","url":"https:\/\/danabiosci.com\/products\/new-product-602237","provider":"Dana Bioscience","version":"1.0","type":"link"}