anti- USP34 antibody

anti- USP34 antibody

Product Name

USP34 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

IMMUNOGEN INFORMATION

Immunogen

ubiquitin specific peptidase 34

Synonyms

Deubiquitinating enzyme 34, FLJ43910, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34

Observed MW

47 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IP: 1：200-1：2000; IHC: 1：20-1：200

UNIPROT INFORMATION

UniProt ID

Q70CQ2

IMAGES