{"product_id":"new-product-585775","title":"anti- THRAP3 antibody","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTHRAP3 antibody\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e100µg\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eliquid\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eRabbit\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003epolyclonal\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIgG\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eInvolved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex(EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons(PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC\/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC\/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1\/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL\/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes(PubMed:24043798).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003ethyroid hormone receptor associated protein 3\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTRAP150\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e109-130 kDa\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eELISA, WB, IF, IHC, IP\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9Y2W1\" data-mce-fragment=\"1\" data-mce-href=\"http:\/\/www.uniprot.org\/uniprot\/Q9Y2W1\"\u003eQ9Y2W1\u003c\/a\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eIMAGES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab08673.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eImmunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab08673(THRAP3 Antibody) at dilution of 1:50\u003c\/div\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image3\/FNab08673.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eIP Result of anti-THRAP3 (IP:FNab08673, 4ug; Detection:FNab08673 1:500) with HeLa cells lysate 600ug.\u003c\/div\u003e\n\u003cfigure class=\"w-full md:w-2\/3 p-2 border relative\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab08673.jpg\"\u003e\u003c\/figure\u003e\n\u003cdiv class=\"w-full md:pl-8 pt-4 md:pt-0 md:w-1\/3\"\u003eHeLa cells were subjected to SDS PAGE followed by western blot with FNab08673(THRAP3 antibody) at dilution of 1:500\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg \/ Rabbit \/ polyclonal","offer_id":47550023205144,"sku":"FNab08673","price":280.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/fine_test_logo_73364603-1f62-417f-987b-b997339d0f16.jpg?v=1705729690","url":"https:\/\/danabiosci.com\/products\/new-product-585775","provider":"Dana Bioscience","version":"1.0","type":"link"}