{"product_id":"new-product-581302","title":"VE-Cadherin Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.\u003c\/p\u003e\n\u003cp\u003eThe VE-Cadherin Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of VE-Cadherin protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.\u003cbr\u003e\u003cbr\u003eVE-Cadherin, also known as vascular endothelial cadherin or CDH5, is a transmembrane glycoprotein that plays a crucial role in the maintenance of endothelial cell integrity and vascular development. It is predominantly expressed in endothelial cells and is involved in cell-cell adhesion, regulating vascular permeability, and angiogenesis.\u003cbr\u003e\u003cbr\u003eThe VE-Cadherin Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the native and denatured forms of VE-Cadherin protein, enabling accurate and reliable detection in both normal and pathological tissues.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated and characterized to ensure consistent and reproducible results. It exhibits minimal cross-reactivity with other related proteins, ensuring specificity in target detection. Additionally, it demonstrates excellent sensitivity, allowing for the detection of low levels of VE-Cadherin expression.\u003cbr\u003e\u003cbr\u003eThe VE-Cadherin Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex preparation steps. It is provided in a convenient format, allowing for easy storage and handling.\u003cbr\u003e\u003cbr\u003eIn summary, the VE-Cadherin Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of VE-Cadherin protein expression. With its exceptional performance and ease of use, it is an essential reagent for researchers and scientists studying vascular biology, angiogenesis, and endothelial cell function.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548457386264,"sku":"BT-AP15453","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_406de289-3154-4f1e-bb9f-ad4960332538.png?v=1705694946","url":"https:\/\/danabiosci.com\/products\/new-product-581302","provider":"Dana Bioscience","version":"1.0","type":"link"}