{"product_id":"new-product-581290","title":"Vav(Phospho Tyr174) Polyclonal Antibody","description":"\u003cp\u003eThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK\/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\n\u003cp\u003eIntroducing the VAV(PHOSPHO TYR174) Polyclonal Antibody, a highly specific and sensitive tool for the detection of VAV protein phosphorylated at tyrosine 174. This antibody has been rigorously tested and validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence microscopy. \u003cbr\u003e\u003cbr\u003eThe VAV(PHOSPHO TYR174) Polyclonal Antibody is produced using state-of-the-art techniques and is of the highest quality, ensuring reliable and reproducible results. It is designed to recognize the phosphorylated form of VAV protein at tyrosine 174, making it an ideal tool for studying the regulation of VAV signaling pathways. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient format, with a concentration of 1 mg\/mL, and is available in various sizes to suit your experimental needs. It has been extensively characterized and validated for specificity, sensitivity, and reproducibility, ensuring that you can trust the results of your experiments. \u003cbr\u003e\u003cbr\u003eIn summary, the VAV(PHOSPHO TYR174) Polyclonal Antibody is a valuable tool for researchers studying VAV signaling pathways. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its quality and reliability ensure that you can trust your results.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548455715096,"sku":"BT-AP15431","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_94fef773-a93e-4d62-a9e0-a9ad56c947f3.png?v=1705694893","url":"https:\/\/danabiosci.com\/products\/new-product-581290","provider":"Dana Bioscience","version":"1.0","type":"link"}