{"product_id":"new-product-581207","title":"UB2D1 Polyclonal Antibody","description":"\u003cp\u003eThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe UB2D1 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of UB2D1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human UB2D1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards UB2D1 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.\u003cbr\u003e\u003cbr\u003eThe UB2D1 Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications.\u003cbr\u003e\u003cbr\u003eThe UB2D1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting UB2D1 protein in various human tissues and cell lines. It has been shown to be highly effective in detecting endogenous UB2D1 protein expression levels in Western blotting and immunohistochemistry assays. Additionally, this antibody has been used successfully in ELISA assays to quantify UB2D1 protein levels in biological samples.\u003cbr\u003e\u003cbr\u003eIn summary, the UB2D1 Polyclonal Antibody is a reliable and high-quality immunological reagent that is ideal for the detection and quantification of UB2D1 protein in various biological samples. Its high specificity and sensitivity make it an essential tool for researchers studying the role of UB2D1 in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548428943640,"sku":"BT-AP15277","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f6964f32-2676-44cd-9eff-b85e126bc280.png?v=1705694454","url":"https:\/\/danabiosci.com\/products\/new-product-581207","provider":"Dana Bioscience","version":"1.0","type":"link"}