{"product_id":"new-product-581108","title":"Topo II alpha(Phospho Ser1106) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also pla\u003c\/p\u003e\n\u003cp\u003eThe TOPO II ALPHA(PHOSPHO SER1106) Polyclonal Antibody is a highly specialized product designed for the detection and analysis of the TOPO II ALPHA protein. This antibody is specifically designed to target the phosphorylated serine residue at position 1106 of the TOPO II ALPHA protein, making it an ideal tool for researchers studying the regulation and function of this important protein.\u003cbr\u003e\u003cbr\u003eThe TOPO II ALPHA(PHOSPHO SER1106) Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure the highest level of specificity and sensitivity. This antibody is suitable for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eWith its high specificity and sensitivity, the TOPO II ALPHA(PHOSPHO SER1106) Polyclonal Antibody is an essential tool for researchers studying the role of the TOPO II ALPHA protein in a variety of biological processes. Whether you are investigating the mechanisms of DNA replication, transcription, or repair, this antibody is sure to provide valuable insights into the function of this important protein.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548404924696,"sku":"BT-AP15069","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_22e4eed6-e74d-43af-9fa1-889a53fb426b.png?v=1705693934","url":"https:\/\/danabiosci.com\/products\/new-product-581108","provider":"Dana Bioscience","version":"1.0","type":"link"}