{"product_id":"new-product-580934","title":"TAL1(Phospho Ser122) Polyclonal Antibody","description":"\u003cp\u003ealternative products:The splicing pattern is cell-lineage dependent,disease:A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.,The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.,Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.,PTM:Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia.,PTM:Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.,Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms heterodimers with TCF3. Binds to the LIM domain containing protein LMO2 and to DRG1. Can assemble in a complex with LDB1 and LMO2. Component of a TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3.,tissue specificity:Leukemic stem cell.,\u003c\/p\u003e\n\u003cp\u003eThe TAL1(PHOSPHO SER122) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TAL1 protein phosphorylated at serine 122. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe TAL1(PHOSPHO SER122) Polyclonal Antibody exhibits excellent performance in recognizing the phosphorylated form of TAL1 protein at serine 122, making it an invaluable tool for researchers studying the role of TAL1 in cellular processes and signaling pathways. Its high affinity and selectivity enable precise and accurate detection of phosphorylated TAL1, facilitating the investigation of its functional implications in various biological contexts.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and reproducibility. It has been extensively validated using a variety of experimental techniques and has demonstrated exceptional performance in detecting phosphorylated TAL1 protein in both cell lysates and tissue samples.\u003cbr\u003e\u003cbr\u003eThe TAL1(PHOSPHO SER122) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its user-friendly format allows for easy integration into laboratory workflows, ensuring efficient and reliable results.\u003cbr\u003e\u003cbr\u003eIn summary, the TAL1(PHOSPHO SER122) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of phosphorylated TAL1 protein at serine 122. Its exceptional performance, reliability, and ease of use make it an ideal choice for researchers investigating the functional role of TAL1 in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548301902104,"sku":"BT-AP14740","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4dbc2330-4545-40ec-87a4-7f03e5235a4f.png?v=1705693065","url":"https:\/\/danabiosci.com\/products\/new-product-580934","provider":"Dana Bioscience","version":"1.0","type":"link"}