{"product_id":"new-product-580932","title":"Tak1(Phospho Ser439) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the serine\/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1\/TAB1 and MAP3K7P2\/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8\/JNK, MAP2K4\/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e\n\u003cp\u003eThe TAK1(PHOSPHO SER439) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of TAK1 protein phosphorylated at serine 439 residue. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe TAK1(PHOSPHO SER439) Polyclonal Antibody is suitable for various applications, including western blotting, immunoprecipitation, and immunohistochemistry. It has been extensively validated for its performance in detecting TAK1 phosphorylation at serine 439 in a wide range of sample types, including cell lysates and tissue extracts.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity and specificity, this antibody enables researchers to accurately study the role of TAK1 phosphorylation at serine 439 in various cellular processes and signaling pathways. It provides valuable insights into the regulation and function of TAK1, a critical kinase involved in numerous biological processes, including immune response, inflammation, and cell survival.\u003cbr\u003e\u003cbr\u003eThe TAK1(PHOSPHO SER439) Polyclonal Antibody is manufactured under strict quality control standards to ensure consistent and reliable results. It is supplied in a convenient format, allowing for easy handling and storage. Each batch of antibody undergoes rigorous testing to guarantee its performance and reliability, providing researchers with confidence in their experimental outcomes.\u003cbr\u003e\u003cbr\u003eIn summary, the TAK1(PHOSPHO SER439) Polyclonal Antibody is a highly specific and sensitive tool that facilitates the investigation of TAK1 phosphorylation at serine 439. Its exceptional performance and reliability make it an ideal choice for researchers studying the intricate mechanisms of TAK1 signaling and its implications in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548301377816,"sku":"BT-AP14735","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_55d9ca42-4b39-4138-824b-22f08982c759.png?v=1705693042","url":"https:\/\/danabiosci.com\/products\/new-product-580932","provider":"Dana Bioscience","version":"1.0","type":"link"}