{"product_id":"new-product-580829","title":"Stat5(Phospho Ser726\/731) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL\/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1\/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been\u003c\/p\u003e\n\u003cp\u003eThe STAT5(PHOSPHO SER726\/731) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated STAT5 at serine residues 726 and 731. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe phosphorylation of STAT5 at serine residues 726 and 731 plays a crucial role in the activation and regulation of STAT5 signaling pathway. By targeting these phosphorylation sites, this antibody enables researchers to investigate the activation status of STAT5 and its involvement in various cellular processes, including cell proliferation, differentiation, and survival.\u003cbr\u003e\u003cbr\u003eThe STAT5(PHOSPHO SER726\/731) Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into experimental workflows. It is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins. Additionally, it is suitable for use in both human and animal samples, making it a versatile tool for diverse research applications.\u003cbr\u003e\u003cbr\u003eIn summary, the STAT5(PHOSPHO SER726\/731) Polyclonal Antibody is a valuable resource for researchers studying STAT5 signaling pathway. Its high specificity, sensitivity, and compatibility with multiple applications make it an essential tool for investigating the role of phosphorylated STAT5 in cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548255666456,"sku":"BT-AP14545","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f0e01859-96d4-4f47-a6f3-5a9857024c7a.png?v=1705692536","url":"https:\/\/danabiosci.com\/products\/new-product-580829","provider":"Dana Bioscience","version":"1.0","type":"link"}