{"product_id":"new-product-580704","title":"SMC1(Phospho Ser957) Polyclonal Antibody","description":"\u003cp\u003eProper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Altern\u003c\/p\u003e\n\u003cp\u003eThe SMC1B polyclonal antibody is a highly specific and sensitive tool for the detection and analysis of SMC1B protein expression in various biological samples. This antibody is produced using a polyclonal approach, which ensures a high degree of specificity and sensitivity towards the target protein. The SMC1B polyclonal antibody is designed to recognize the SMC1B protein, a member of the structural maintenance of chromosomes (SMC) family, which plays a crucial role in chromosome cohesion and DNA repair. This antibody is suitable for use in a wide range of applications, including western blotting, immunohistochemistry, and immunofluorescence. The SMC1B polyclonal antibody is rigorously tested to ensure high quality and consistency, making it an ideal choice for researchers and scientists working in the fields of molecular biology, genetics, and cell biology. With its exceptional performance and reliability, the SMC1B polyclonal antibody is an essential tool for the study of SMC1B protein expression and function.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548179349784,"sku":"BT-AP14316","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_ecf7852c-54e1-4b38-9fea-b5dc832172dc.png?v=1705691905","url":"https:\/\/danabiosci.com\/products\/new-product-580704","provider":"Dana Bioscience","version":"1.0","type":"link"}