{"product_id":"new-product-580685","title":"Smad1(Phospho Ser465) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med\u003c\/p\u003e\n\u003cp\u003eIntroducing the SMAD1(PHOSPHO SER465) Polyclonal Antibody, a highly specific and reliable tool for the detection and analysis of SMAD1 protein phosphorylated at serine 465. This antibody has been extensively validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence microscopy.\u003cbr\u003e\u003cbr\u003eThe SMAD1(PHOSPHO SER465) Polyclonal Antibody is produced using state-of-the-art techniques and high-quality materials, ensuring exceptional sensitivity and specificity. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, providing accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is suitable for use in a wide range of research applications, including studies of signal transduction pathways, cell differentiation, and development. Its high specificity and sensitivity make it an ideal tool for investigating the role of SMAD1 in various cellular processes.\u003cbr\u003e\u003cbr\u003eIn summary, the SMAD1(PHOSPHO SER465) Polyclonal Antibody is a valuable tool for researchers seeking to investigate the function and regulation of SMAD1 protein phosphorylation. Its exceptional quality and reliability make it an essential component of any research program focused on signal transduction pathways and cellular differentiation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47548173975832,"sku":"BT-AP14283","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_af8ac622-46b1-4868-9977-c8164d0bd95c.png?v=1705691807","url":"https:\/\/danabiosci.com\/products\/new-product-580685","provider":"Dana Bioscience","version":"1.0","type":"link"}