{"product_id":"new-product-580257","title":"Raf-1(Phospho Ser289) Polyclonal Antibody","description":"\u003cp\u003eThis gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine\/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.\u003c\/p\u003e\n\u003cp\u003eIntroducing the RAF-1 Phospho-Ser289 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of life sciences. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of RAF-1 at serine 289, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision and utilizing state-of-the-art technology, the RAF-1 Phospho-Ser289 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity for the phosphorylated serine 289 residue of RAF-1 guarantees optimal performance in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.\u003cbr\u003e\u003cbr\u003eWith its robust performance, this antibody serves as an invaluable tool for elucidating the role of RAF-1 phosphorylation in diverse biological processes, such as cell proliferation, differentiation, and survival. By facilitating the investigation of RAF-1 signaling cascades, researchers can gain deeper insights into the intricate molecular mechanisms underlying various diseases, including cancer.\u003cbr\u003e\u003cbr\u003eThe RAF-1 Phospho-Ser289 Polyclonal Antibody is meticulously validated to ensure exceptional quality and reliability. Rigorous testing procedures, including peptide blocking assays and immunohistochemical analysis, guarantee the antibody's specificity and accuracy. Furthermore, this antibody is produced using advanced recombinant DNA technology, ensuring batch-to-batch consistency and minimizing any potential variability.\u003cbr\u003e\u003cbr\u003eBT Lab takes pride in delivering cutting-edge research tools, and the RAF-1 Phospho-Ser289 Polyclonal Antibody is no exception. With its exceptional sensitivity, specificity, and reliability, this antibody empowers researchers to unravel the complexities of cellular signaling pathways and pave the way for groundbreaking discoveries in the field of life sciences.\u003cbr\u003e\u003cbr\u003eNote: For detailed information regarding the product's usage, storage conditions, and recommended protocols, please refer to the official product page provided by BT Lab.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547911700760,"sku":"BT-AP13522","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_cb50b14c-4853-491e-9691-7fecfd5015a5.png?v=1705689556","url":"https:\/\/danabiosci.com\/products\/new-product-580257","provider":"Dana Bioscience","version":"1.0","type":"link"}